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Currently, there are no approved on-hand rescue treatments for acute anxiety episodes or panic attacks

There are more than 40 million people in the United States with anxiety disorders. Acute episodes can occur in all major types—generalized anxiety, obsessive-compulsive disorder, post-traumatic stress disorder, social phobia, and panic disorder. Up to 75% of patients with panic disorder will experience an acute panic attack—even though they may be taking daily chronic therapy, these attacks can be terrifying and impact approximately 2.4 million adults annually.
Presently, there are no FDA-approved products indicated for the treatment of acute anxiety episodes.

About NRL-2

  • NRL-2 is being developed as an acute rescue therapy for patients with anxiety who suffer from debilitating acute anxiety episodes, such as panic attacks.*


  • NRL-2 is a proprietary intranasal formulation with Intravail®.


  • NRL-2 is in the initial (formulation) stage of development and presents a worldwide commercial opportunity for Neurelis.

*NRL-2 is an investigational drug candidate being developed for children and adults who require intermittent use of benzodiazepines for acute anxiety episodes and has not been approved by FDA for any indication.